Figure 4: The histopathological findings of all experimental groups. (A) The control group shows normal histological appearance. (B) The acrylamide treated group shows severe degeneration of the renal tubular epithelium (arrowhead), necrosis (arrows), and hyperemia in vessels (star). (C) The group treated with acrylamide and 50 mg/kg naringin shows moderate degeneration of the renal tubular epithelium (arrowheads), moderate necrosis (arrow), and severe hyperemia (star). (D) The group treated with acrylamide and 100 mg/kg naringin shows mild degeneration of the renal tubular epithelium (arrowhead) and moderate hyperemia (star) in vessels. (E) The group treated with 100 mg/kg naringin alone shows a normal renal structure. H&E, Bar: 50 μm; Magnification: ×40. (F-H) Bar graphs show the results of congestion in the vessels, necrosis of the tubular epithelium, and degeneration of the tubular epithelium. The data are expressed as mean ± SEM (n=10) and analyzed by one-way ANOVA followed by t-test. Different letters indicate statistically significant differences, P<0.05.