Figure 1: Spasmogenic and spasmolytic effect of Argemone mexicana (A. mexicana) crude extract on rhythmic contraction of rabbit jejunum fragment. (A) Spasmogenic effect of A. mexicana crude extract at tissue bath concentrations of 0.001-0.3 mg/mL. (B) Blockage of spasmogenic effect of A. mexicana crude extract with atropine (0.3 pM). (C) Spasmolytic effect of standard calcium channel blocker (verapamil). (D) The spasmogenic or spasmolytic effect of the extract in the absence and presence of atropine. Data are presented as mean ± SD (n=5).