Figure 6: Histopathological results of the kidney in mice. (A1-A2) The finasteride group shows hyperemia in the renal arteries (*) and tubular necrosis (TN) in PCT and DCT in the glomeruli, and lymphocytic infiltration (LI) between the tubules. (B, C and D) The treatment groups (100, 200 and 400 mg/kg/day of Origanum vulgare extract) show improved structure of the liver, which is more pronounced at the dose of 400 mg/kg. No tubular necrosis, lymphocyte infiltration, and vascular hyperemia are observed. (E) The normal group shows the normal structure of the tubules, glomeruli, and renal arteries. G: normal glomerulus; BV: blood vessel; PCT: proximal convoluted tubule; DCT: distal convoluted tubule; US: urinary space; DG: glomerular degeneration; CT: collecting tubules; MD: macula densa [A1, A2, B, C, D, and E, PASX100, (scale bar = 100 μm)].