Figure 4: Effect of Origanum vulgare extract on oxidative stress and inflammatory cytokines in finasteride-exposed mice. (A) Serum levels of cytokines including IFN-γ, IL-6, TNF-α, IL-1., IL-10, and IL-12. (B) Serum levels of CAT, NOS, NO, TAS, and MDA. The data are expressed as mean±SD. $P < 0.05, $$P < 0.01 compared with the normal group; *P < 0.05, **P < 0.01 compared with the finasteride group. CAT: catalase; TAS: total antioxidant status; NOS: nitric oxide synthase; MDA: malondialdehyde; NO: nitric oxide; IFN-γ: interferon-γ; IL-6: interleukin-6; TNF-α: tumor necrosis factor-α; IL-1β: interleukin-1β; IL- 10: interleukin-10; IL-12: interleukin-12.