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  Indian J Med Microbiol
 

Figure 1: Effect of p-coumaric acid on histopathological changes of liver tissue in different experimental groups (H&E ×300) (A) The normal control group, and (B) the group receiving p-coumaric acid treatment alone (100 mg/kg/day) show that the liver has a normal architecture. (C) The adriamycin group shows parenchymal necrosis (black arrow), dilatation of sinusoids (white arrow), hepatocyte degeneration (green arrow), eosinophilic cytoplasm (yellow arrow) and inflammatory cells (blue arrow). (D) The group treated with adriamycin and p-coumaric acid alleviates the damages induced by adriamycin.

Figure 1: Effect of <i>p</i>-coumaric acid on histopathological changes of liver tissue in different experimental groups (H&E ×300) (A) The normal control group, and (B) the group receiving <i>p</i>-coumaric acid treatment alone (100 mg/kg/day) show that the liver has a normal architecture. (C) The adriamycin group shows parenchymal necrosis (black arrow), dilatation of sinusoids (white arrow), hepatocyte degeneration (green arrow), eosinophilic cytoplasm (yellow arrow) and inflammatory cells (blue arrow). (D) The group treated with adriamycin and <i>p</i>-coumaric acid alleviates the damages induced by adriamycin.