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  Indian J Med Microbiol
 

Figure 3: Two-dimensional binding site interaction models. (A) ibuprofen with COX-1; (B) paracetamol with COX-1; (C) phloridzin with COX-1; (D) ibuprofen with COX-2; (E) paracetamol with COX-2; (F) phloridzin with COX-2; (G) ibuprofen with PGES-1; (H) paracetamol with PGES-1; (I) phloridzin with PGES-1; (J) ibuprofen with 5-LOX; (K) paracetamol with 5-LOX; (L) phloridzin with 5-LOX. COX-1 and COX-2: cyclooxygenase-1 and 2, PGES-1: prostaglandin E synthase-1, 5-LOX: 5-lipoxygenase.

Figure 3: Two-dimensional binding site interaction models. (A) ibuprofen with COX-1; (B) paracetamol with COX-1; (C) phloridzin with COX-1; (D) ibuprofen with COX-2; (E) paracetamol with COX-2; (F) phloridzin with COX-2; (G) ibuprofen with PGES-1; (H) paracetamol with PGES-1; (I) phloridzin with PGES-1; (J) ibuprofen with 5-LOX; (K) paracetamol with 5-LOX; (L) phloridzin with 5-LOX. COX-1 and COX-2: cyclooxygenase-1 and 2, PGES-1: prostaglandin E synthase-1, 5-LOX: 5-lipoxygenase.