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  Indian J Med Microbiol
 

Figure 4: AMPK-dependent modulation by pear pomace water extract (PPWE) in 3T3-L1 cells. 3T3-L1 cells were pretreated with compound C for l h, and then differentiated with PBS or PPWE 250 μg/mL for 8 d. (A) Lipid content, (B) Protein expression of p-AMPK/AMPK, (C) Protein expression of C/EBPa, PPAR-γ, SREBP-1c, FAS, and p-ACC/ACC. Means with different letters are significantly different by Duncan’s multiple range test (P <0.05). C: PBS, PPWE: pear pomace water extract (250 μg/mL), 1 μM CC + PPWE: pear pomace water extract 250 μg/mL with 1 μM compound C.

Figure 4: AMPK-dependent modulation by pear pomace water extract (PPWE) in 3T3-L1 cells. 3T3-L1 cells were pretreated with compound C for l h, and then differentiated with PBS or PPWE 250 μg/mL for 8 d. (A) Lipid content, (B) Protein expression of p-AMPK/AMPK, (C) Protein expression of C/EBPa, PPAR-γ, SREBP-1c, FAS, and p-ACC/ACC. Means with different letters are significantly different by Duncan’s multiple range test (<i>P</i> <0.05). C: PBS, PPWE: pear pomace water extract (250 μg/mL), 1 μM CC + PPWE: pear pomace water extract 250 μg/mL with 1 μM compound C.