Figure 4: Photomicrographs of renal sections from different studied groups (H & E, ×40). A: the control group shows a normal renal architecture including Bowman’s capsule, glomerulus, mesangium, proximal convoluted tubule (PCT) and distal convoluted tubule. B: the CCl4 treated group shows the loss of brush border on tubular epithelial cells, hydropic degeneration in the tubule epithelium, karyolysis, tubular dilatation, tubular necrosis, epithelial lining necrosis and shrinkage of the Bowman’s capsule size. C: the Cystone® treated group shows the restoration of renal architecture. Bowman’s capsule is normal in size and PCT regains normal. D: BSVT (25 mg/kg) treated group shows normal PCT with a brush border on tubular epithelium cells and mild karyolysis and tubular necrosis is observed. E: BSVT (50 mg/kg) treated group shows normal PCT with a brush border on tubular epithelium cells with marginal tubular necrosis. F: BSVT (100 mg/kg) treated group shows the restoration of renal architectures, which is strikingly similar to that of the normal control group except for mild epithelial cell necrosis.