Figure 1: Depression-like behaviors induced by LPS in mice. Mice were injected with 0.6 or 1.0 mg/kg (i.p.) LPS. Immobility time for 5 min in forced swimming test (A), body weight (B), travel distance (C), and the crossing number for 5 min in open field test (D) were measured (mean ± SD, n =12). aP < 0.05 vs. the control group. LPS: lipopolysaccharide.