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  Indian J Med Microbiol
 

Figure 1: Histological sections of kidney from normal rats, CCl4 intoxicated rats and CCl4 intoxicated rats treated with resveratrol (H&E staining; A, B, E, G, H, at ×3 000 magnification, and C, D, F at ×750 magnification). Normal renal histoarchitecture with well-organized tubules and normal glomerulus and Bowman's capsule is observed in (A) healthy control, (B) olive oil, (C) olive oil + resveratrol 10 mg/kg, and (D) olive oil + resveratrol 20 mg/kg groups; (E) The CCl4 group shows severe tubular degeneration and necrosis accompanied with cytoplasmic vacuoles (arrows), and (F) severe infiltration of mononuclear cell in the interstitial tissue (stars); (G) The CCl4 intoxicated rats treated with 10 mg/kg resveratrol show mild tubular atrophy without cytoplasmic vacuoles; (H) The CCl4 intoxicated rats treated with 20 mg/kg resveratrol show well-organized proximal and distal convoluted tubules which is comparable with the normal group.

Figure 1: Histological sections of kidney from normal rats, CCl4 intoxicated rats and CCl4 intoxicated rats treated with resveratrol (H&E staining; A, B, E, G, H, at ×3 000 magnification, and C, D, F at ×750 magnification). Normal renal histoarchitecture with well-organized tubules and normal glomerulus and Bowman's capsule is observed in (A) healthy control, (B) olive oil, (C) olive oil + resveratrol 10 mg/kg, and (D) olive oil + resveratrol 20 mg/kg groups; (E) The CCl4 group shows severe tubular degeneration and necrosis accompanied with cytoplasmic vacuoles (arrows), and (F) severe infiltration of mononuclear cell in the interstitial tissue (stars); (G) The CCl4 intoxicated rats treated with 10 mg/kg resveratrol show mild tubular atrophy without cytoplasmic vacuoles; (H) The CCl4 intoxicated rats treated with 20 mg/kg resveratrol show well-organized proximal and distal convoluted tubules which is comparable with the normal group.